Determination optical properties of tissue-like phantoms using diffuse reflectance and transmittance spectroscopy

Huihui Lu; Jacqueline Gunther; Stefan Andersson-Engels

doi:10.1117/12.2501183

23 October 2018 Determination optical properties of tissue-like phantoms using diffuse reflectance and transmittance spectroscopy

Huihui Lu, Jacqueline Gunther, Stefan Andersson-Engels

Author Affiliations +

Proceedings Volume 10820, Optics in Health Care and Biomedical Optics VIII; 108202X (2018) https://doi.org/10.1117/12.2501183
Event: SPIE/COS Photonics Asia, 2018, Beijing, China

Abstract

We present a simple, convenient fibre-optics probe system for the determination optical properties of tissue-like liquid phantoms based on diffuse reflectance and transmittance measurements at the wavelength of visible-near-infrared region. The method combined Monte Carlo simulations, multiple polynomial regression and a Newton-Raphson algorithm for solving nonlinear equation system. In the range of optical properties of phantom with the μ_a at 0 – 0.5 cm^-1 and the μs’ at 3 – 45 cm^-1, the mean prediction error at 630 nm was 1.91 % for μ_s’ and 7.51 % for μ_a. The performance of the method is further tested by predictive error and validated using similar matrix of milk-ink phantoms on reflectance and transmittance.

Citation Download Citation

Huihui Lu, Jacqueline Gunther, and Stefan Andersson-Engels "Determination optical properties of tissue-like phantoms using diffuse reflectance and transmittance spectroscopy ", Proc. SPIE 10820, Optics in Health Care and Biomedical Optics VIII, 108202X (23 October 2018); https://doi.org/10.1117/12.2501183

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