MHz OCT angiography for 60 degree retinal imaging and microscopic choriocapillaris imaging

M. Niederleithner; L. Ginner; M. Salas; H. Ren; M. A. Arain; R. Williams; W. Drexler; R. A. Leitgeb; T. Schmoll

doi:10.1117/12.2527079

19 July 2019 MHz OCT angiography for 60 degree retinal imaging and microscopic choriocapillaris imaging

M. Niederleithner, L. Ginner, M. Salas, H. Ren, M. A. Arain, R. Williams, W. Drexler, R. A. Leitgeb, T. Schmoll

Proceedings Volume 11078, Optical Coherence Imaging Techniques and Imaging in Scattering Media III; 110781D (2019) https://doi.org/10.1117/12.2527079
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

The choriocappilaris layer is considered to be one of the first retinal layers affected in age related macular degeneration and other retinal diseases [1]. Imaging this fine vascular layer below the retinal pigment epithelium (RPE) with optical coherence tomography angiography (OCTA) has been very challenging due to the high scattering and absorption of the RPE. In OCTA higher inter B-scan times increase the sensitivity for slow motion and hence improve the contrast of fine vessels. However, it was demonstrated that for the choriocappilaris the opposite is the case [2]. Novel swept source laser technology enables acquiring images at A-scan-rates of 1.7 million A-scans per second, which is approx. 17 times faster than the fastest commercially available OCT devices [3, 4]. OCTA images of the human macula with different inter B-scan times were acquired and compared. The same prototype system was also used to acquire single shot wide-field OCTA images with up to 60 degree field of view.

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M. Niederleithner, L. Ginner, M. Salas, H. Ren, M. A. Arain, R. Williams, W. Drexler, R. A. Leitgeb, and T. Schmoll "MHz OCT angiography for 60 degree retinal imaging and microscopic choriocapillaris imaging", Proc. SPIE 11078, Optical Coherence Imaging Techniques and Imaging in Scattering Media III, 110781D (19 July 2019); https://doi.org/10.1117/12.2527079

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KEYWORDS

Optical coherence tomography

Retina

Angiography

Retinal scanning

Image segmentation

Scanners

Laser development

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