Microfluidics imaging for label-free metrology of individual biological cells

Yuval Atzitz; Itay Barnea; Natan T. Shaked

doi:10.1117/12.2593398

20 June 2021 Microfluidics imaging for label-free metrology of individual biological cells

Yuval Atzitz, Itay Barnea, Natan T. Shaked

Author Affiliations +

Proceedings Volume 11786, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V; 117860E (2021) https://doi.org/10.1117/12.2593398
Event: SPIE Optical Metrology, 2021, Online Only

Abstract

We propose a label-free metrology technique that can perform analysis of live individual cells while they are growing individually in droplets. The cells first flow in a microfluidics device and imaged using interferometry. At the end of this device the droplets with the cells accumulate and then the cells can be monitored over time. The device presents the possibility for both high-throughput label-free analysis of individual biological cells and tracking their long-term development.

Conference Presentation

Citation Download Citation

Yuval Atzitz, Itay Barnea, and Natan T. Shaked "Microfluidics imaging for label-free metrology of individual biological cells", Proc. SPIE 11786, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials V, 117860E (20 June 2021); https://doi.org/10.1117/12.2593398

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