Theoretical analysis of dynamic variation of temperature-dependent optical properties in the response of laser-irradiated tissue

Sohi Rastegar; Massoud Motamedi

doi:10.1117/12.17634

1 June 1990 Theoretical analysis of dynamic variation of temperature-dependent optical properties in the response of laser-irradiated tissue

Sohi Rastegar, Massoud Motamedi

Author Affiliations +

Proceedings Volume 1202, Laser-Tissue Interaction; (1990) https://doi.org/10.1117/12.17634
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

Theoretical modeling of the processes oflight and temperature distribution is rapidly developing both as a qualitative as well as a qtiantitative tool for the understanding of laser light interaction with tissue. Many applications oflasers in medicine involve volumetric coagulation of tissue. In these processes laser light incident on tissue is absorbed and scattered by tissue chromophores and subsequently converted to thermal energy resulting in a temperature rise in tissue. It is well known that elevation of temperature can cause tissue coagulation which is, in most tissues, accompanied by a change in optical properties of tissue (Gourgouliatos [1987], Spears et al. [1988]; Jacques and Gaeeni [1989]). The results by Jacques and Gaeeni [1989] provide a quantitative data for absorption and scattering coefficients of dog myocardium as a function of temperature at selected wavelengths. Parametric study of the effect of variation of optical properties on heat generation, temperature distribution, and ablation rate has been done by Motamedi et a! [1989] and Rastegar et al. [1989]. However, these and other analyses ( e.g. Armon and Laufer [1985], McKenzie [1986], Jacques and PraM [1987] )of temperature disiribution in tissue traditionally have not considered the role of dynamic variation of of the optical properties with temperature. This paper presents a method to analyze this effect and explores its potential impact on laser dosimetry prescription for laser applications involving coagulation of tissue.

Citation Download Citation

Sohi Rastegar and Massoud Motamedi "Theoretical analysis of dynamic variation of temperature-dependent optical properties in the response of laser-irradiated tissue", Proc. SPIE 1202, Laser-Tissue Interaction, (1 June 1990); https://doi.org/10.1117/12.17634

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