Ultrafast ablation of bone tissue: process optimisation and species dependence

Laura Gemini; Samy Al-Bourgol; Marc Faucon; Guillaume Machinet; Rainer Kling

doi:10.1117/12.2657976

17 March 2023 Ultrafast ablation of bone tissue: process optimisation and species dependence

Laura Gemini, Samy Al-Bourgol, Marc Faucon, Guillaume Machinet, Rainer Kling

Proceedings Volume 12411, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XXIII; 1241106 (2023) https://doi.org/10.1117/12.2657976
Event: SPIE LASE, 2023, San Francisco, California, United States

Abstract

Femtosecond laser processing of bone tissue has shown great potential for osteotomy procedures where high precision cutting and the preservation of bone tissue functions are of primary importance. Nonetheless, the ablation rates related to this kind of process still remain too low for this technology to be exploitable in a real surgical procedure. Moreover, the strong dependence of the process outcomes from factors such as the processing environment, the type of pre-processing and post-processing treatment of the bone tissue, the species of the processed animal and the bone part itself, stall the full development and advancement of this technique. This study highlights the key role of the anatomical region (femur, tibia, etc.) and species (pig, chicken, etc.) of the investigated bone tissue samples to provide a solid reference on the impact of the choice of types of samples on laser ablation studies of bone tissue. Results show that it is essential to choose the best animal model for a specific case study, which depends to a large extent on the objectives of the research subject. There are no perfect animal models: the selection of one animal model is often associated with its similarity to the human model because the goal is the validation of experiments in clinical setting. However, most studies do not take these variabilities into account in their conclusions.

Conference Presentation

Citation Download Citation

Laura Gemini, Samy Al-Bourgol, Marc Faucon, Guillaume Machinet, and Rainer Kling "Ultrafast ablation of bone tissue: process optimisation and species dependence", Proc. SPIE 12411, Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications XXIII, 1241106 (17 March 2023); https://doi.org/10.1117/12.2657976

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