Plasmonic nanostructures based on novel metamolecular units for biological samples investigation

Massimo Rippa; Valentina Marchesano; Ambra Vestri; Domenico Sagnelli; Giovanna Fusco; Joseph Zyss; Jun Zhou; Lucia Petti

doi:10.1117/12.2665256

31 May 2023 Plasmonic nanostructures based on novel metamolecular units for biological samples investigation

Massimo Rippa, Valentina Marchesano, Ambra Vestri, Domenico Sagnelli, Giovanna Fusco, Joseph Zyss, Jun Zhou, Lucia Petti

Author Affiliations +

Proceedings Volume 12572, Optical Sensors 2023; 1257203 (2023) https://doi.org/10.1117/12.2665256
Event: SPIE Optics + Optoelectronics, 2023, Prague, Czech Republic

Abstract

Development of novel plasmonic nanopatterns is of great interest for various applications, including chemical and biological analysis. Systems based on gold nanoelements have been designed and tested in several research works for the study and detection of various kinds of biological analytes, giving appreciable results. Plasmonic properties associated to the nanostructure can be tuned by changing the size and the shape of the nanoparticles or the periodicity or, more in general, the geometry of the nanopattern. These features are key to many applications aiming at signal enhancement and low threshold sensing. In this work we present a study of periodic arrangements of novel plasmonic metamolecular unit cells made of triangular nanoelements. Nanostructures analyzed were fabricated using electron beam lithography technique (EBL) that allows to create patterns with high accuracy and repeatability. Morphological analysis was realized by Scanning Electron Microscopy (SEM) and their plasmonic properties were studied and compared using experimental set-up for Surface Plasmon Resonance (SPR) and Surface Enhanced Raman Spectroscopy (SERS) measurements. We tested the sensing performance of our nanostructures by analyzing the SARS-CoV-2 (COVID-19) Spike Antibody (3525) getting its molecular fingerprint. Our results suggest that these plasmonic patterns are promising to develop highly sensitive nanosensors for the detection of biological analytes.

Conference Presentation

Citation Download Citation

Massimo Rippa, Valentina Marchesano, Ambra Vestri, Domenico Sagnelli, Giovanna Fusco, Joseph Zyss, Jun Zhou, and Lucia Petti "Plasmonic nanostructures based on novel metamolecular units for biological samples investigation", Proc. SPIE 12572, Optical Sensors 2023, 1257203 (31 May 2023); https://doi.org/10.1117/12.2665256

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available