Ultrafast imaging of vascular tissue ablation by an XeCl excimer laser

Walter Neu; Ralf Nyga; Christian Tischler M.D.; Karl Konstantin Haase M.D.; Karl R. Karsch M.D.

doi:10.1117/12.44015

1 May 1991 Ultrafast imaging of vascular tissue ablation by an XeCl excimer laser

Walter Neu, Ralf Nyga, Christian Tischler M.D., Karl Konstantin Haase M.D., Karl R. Karsch M.D.

Proceedings Volume 1425, Diagnostic and Therapeutic Cardiovascular Interventions; (1991) https://doi.org/10.1117/12.44015
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

Ablation and tissue removal of normal and atherosclerotic arterial wall by pulses of λ = 308 nm laser radiation have been probed by visible pulsed dye laser radiation. Photographs have been taken where the samples are irradiated in saline solution. The pulsewidth of the ablating XeCl excimer laser is about Δτ = 30 ns FWHM. The pulses have been transmitted through a fused silica fiber with a core diameter of 600 micrometers . The pulse energy was set to 20 mJ at the distal end of the fiber corresponding to a fluence of 7.5 J/cm2, which is well above the ablation threshold. Visible radiation of a dye laser operated at a wavelength of λ = 580 nm (Δτ ~ 10 ns FWHM) is used to illuminate the tissue surface and the ablation plume. The delay time of the probing pulses with respect to the 308 nm pulses is varied in the nanosecond range up to several hundred microseconds. The ablation process and the resulting plume above the tissue surface are recorded with a CCD camera attached to a PC-based image-processing system. All samples under investigation were fresh human cadaver aortic and femoral artery specimens (less than or equal to 48 h), which had been shock-frozen. The arterial segments showed different types of lipid rich and calcified plaques.

Citation Download Citation

Walter Neu, Ralf Nyga, Christian Tischler M.D., Karl Konstantin Haase M.D., and Karl R. Karsch M.D. "Ultrafast imaging of vascular tissue ablation by an XeCl excimer laser", Proc. SPIE 1425, Diagnostic and Therapeutic Cardiovascular Interventions, (1 May 1991); https://doi.org/10.1117/12.44015

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