Photosensitive liposomes as potential drug delivery vehicles for photodynamic therapy

Christopher G. Morgan; A. C. Mitchell; R. K. Chowdhary

doi:10.1117/12.48220

1 November 1991 Photosensitive liposomes as potential drug delivery vehicles for photodynamic therapy

Christopher G. Morgan, A. C. Mitchell, R. K. Chowdhary

Proceedings Volume 1525, Future Trends in Biomedical Applications of Lasers; (1991) https://doi.org/10.1117/12.48220
Event: MedTech '91, 1991, Berlin, Germany

Abstract

Light-sensitive liposomes incorporating a photochromic phospholipid (Bis-Azo PC) have been developed which exhibit light-activated release of entrapped contents and intervesicular fusion. The trapping and light-induced release of inorganic ions, fluorescent market dyes, and the antitumor drug methotrexate have been demonstrated. These results are discussed together with some of the potential therapeutic applications of light-sensitive liposomes.

Citation Download Citation

Christopher G. Morgan, A. C. Mitchell, and R. K. Chowdhary "Photosensitive liposomes as potential drug delivery vehicles for photodynamic therapy", Proc. SPIE 1525, Future Trends in Biomedical Applications of Lasers, (1 November 1991); https://doi.org/10.1117/12.48220

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