In vivo light dosimetry during superficial photodynamic therapy

Emma J. Hudson; Mark R. Stringer; F. Cairnduff; Michael A. Smith

doi:10.1117/12.168712

1 March 1994 In vivo light dosimetry during superficial photodynamic therapy

Emma J. Hudson, Mark R. Stringer, F. Cairnduff, Michael A. Smith

Proceedings Volume 2078, Photodynamic Therapy of Cancer; (1994) https://doi.org/10.1117/12.168712
Event: Europto Biomedical Optics '93, 1993, Budapest, Hungary

Abstract

The depth distribution of 630 nm laser light has been measured for ten patients during the photodynamic therapy of skin lesions by the application of topical 5-aminolaevulinic acid followed by surface illumination. Results show that the light distribution can be described by the diffusion theory. The values of effective attenuation coefficient obtained for each lesion are in close agreement (0.352 mm^-1 +/- 8%) but the K value, used to describe sub-surface fluence build-up, varies between 0.12 and 8.23, although similar values are obtained for the same type of lesion.

Citation Download Citation

Emma J. Hudson, Mark R. Stringer, F. Cairnduff, and Michael A. Smith "In vivo light dosimetry during superficial photodynamic therapy", Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); https://doi.org/10.1117/12.168712

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