Role of dynamic changes in blood perfusion and optical properties in thermal coagulation of the prostate

Beop-Min Kim; Steven L. Jacques; Sohi Rastegar; Sharon L. Thomsen M.D.; Massoud Motamedi

doi:10.1117/12.209911

22 May 1995 Role of dynamic changes in blood perfusion and optical properties in thermal coagulation of the prostate

Beop-Min Kim, Steven L. Jacques, Sohi Rastegar, Sharon L. Thomsen M.D., Massoud Motamedi

Author Affiliations +

Proceedings Volume 2391, Laser-Tissue Interaction VI; (1995) https://doi.org/10.1117/12.209911
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

The dynamic evolution of the coagulation front in laser irradiated prostate tissue is simulated using a nonlinear finite element method (NFEM) which takes into account the temperature and thermal damage dependence of blood perfusion rate and optical properties. Using this nonlinear model, it was found that the hyperemic ring formed at the periphery of the coagulation front reduces heat penetration significantly and the increased scattering near the tissue surface reduces the light energy deposition in the deep region. The final damage depth would be overestimated by about 50% if the effect of temperature and damage dependence of blood perfusion and optical properties modeling is disregarded.

Citation Download Citation

Beop-Min Kim, Steven L. Jacques, Sohi Rastegar, Sharon L. Thomsen M.D., and Massoud Motamedi "Role of dynamic changes in blood perfusion and optical properties in thermal coagulation of the prostate", Proc. SPIE 2391, Laser-Tissue Interaction VI, (22 May 1995); https://doi.org/10.1117/12.209911

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