Photosensitizer for PDT based on phosphonate phthalocyanine derivative

Gennadii A. Meerovich; Eugeny A. Lukyanets; Olga A. Yuzhakova; Oleg L. Kaliya; Georgy N. Vorozhtsov; Victor B. Loschenov; Nadezgda L. Torshina; Alexander A. Stratonnikov; Eugenia A. Kogan

doi:10.1117/12.260769

4 December 1996 Photosensitizer for PDT based on phosphonate phthalocyanine derivative

Gennadii A. Meerovich, Eugeny A. Lukyanets, Olga A. Yuzhakova, Oleg L. Kaliya, Georgy N. Vorozhtsov, Victor B. Loschenov, Nadezgda L. Torshina, Alexander A. Stratonnikov, Eugenia A. Kogan

Author Affiliations +

Proceedings Volume 2924, Photochemotherapy: Photodynamic Therapy and Other Modalities II; (1996) https://doi.org/10.1117/12.260769
Event: BiOS Europe '96, 1996, Vienna, Austria

Abstract

It is very important to develop new sensitizer which could be efficiently excited at wavelengths exceeding 685 nm where own tissue absorption can be neglected. We have synthesize water soluble phthalocyanine derivative having phosphonate groups as substituents in macrocycle. New sensitizer efficiently absorbs in spectral range 685 - 710 nm. It exhibits intense fluorescence in range 690 -720 nm. The photodynamic activity of new sensitizer is higher than in the case of sulfonated aluminum phthalocyanine.

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Gennadii A. Meerovich, Eugeny A. Lukyanets, Olga A. Yuzhakova, Oleg L. Kaliya, Georgy N. Vorozhtsov, Victor B. Loschenov, Nadezgda L. Torshina, Alexander A. Stratonnikov, and Eugenia A. Kogan "Photosensitizer for PDT based on phosphonate phthalocyanine derivative", Proc. SPIE 2924, Photochemotherapy: Photodynamic Therapy and Other Modalities II, (4 December 1996); https://doi.org/10.1117/12.260769

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