In this paper, we showed that the photon-cell interaction of low intensity laser effects on cells is non-resonant. Although the non-resonant interaction itself is extraordinarily weak, it can be amplified by the coherent interaction. We then put forward the biological information model of low intensity laser (BIML) on cells and the biological information transformation model (BITML). According to BIML: laser couples with intracellular messenger through the chromophore absorption in the cell membrane: cold-color (green, blue, violet) actives cAMP photophodiesterase through Gi protein or activates phospholipase C through Gq protein, or actives one of receptor-linked enzyme: cAMP$ARDN; hot-color (red, orange, yellow) activates adenylate cyclase through Gs protein: cAMP$ARUP. According to BITML, if the laser irradiation dose is greater than the corresponding threshold value, its function would be the function of its complementary color under the non- damage condition. Their successful applications at the cellular level showed that BIML and BITML hold for laser-cell interaction.
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