Application of low-scattering photon correlation spectroscopy for blood monitoring

Igor Victorovich Meglinski; Alexander N. Korolevich; Douglas A. Greenhalgh

doi:10.1117/12.447141

31 October 2001 Application of low-scattering photon correlation spectroscopy for blood monitoring

Igor Victorovich Meglinski, Alexander N. Korolevich, Douglas A. Greenhalgh

Proceedings Volume 4432, Diagnostic Optical Spectroscopy in Biomedicine; (2001) https://doi.org/10.1117/12.447141
Event: European Conferences on Biomedical Optics, 2001, Munich, Germany

Abstract

Extension of the photon correlation spectroscopy (PCS) technique in low scattering regime was employed to the samples of whole blood studied. A few times scattered light from a weak helium-neon laser beam incident on the cuvette with the blood sample was detected by a photo-multiplier, and both temporal intensity autocorrelation functions and power spectra were measured with digital autocorrelator and spectrum analyzer. The potentialities of the qualitative and quantitative determining of the structural characteristics of blood elements are demonstrated. To analyze the blood samples we propose to use the PCS technique extended for the transition regime of scattering from single to multiple. The studies made permits the use of the technique for the in vitro clinical blood testing.

Citation Download Citation

Igor Victorovich Meglinski, Alexander N. Korolevich, and Douglas A. Greenhalgh "Application of low-scattering photon correlation spectroscopy for blood monitoring", Proc. SPIE 4432, Diagnostic Optical Spectroscopy in Biomedicine, (31 October 2001); https://doi.org/10.1117/12.447141

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