Temperature controlled CO2 laser soldering of pig cornea

Eyal Strassmann M.D.; Nino Loya; Dan D. Gaton M.D.; Avi Ravid; Noam Kariv; Dov Weinberger M.D.; Abraham Katzir

doi:10.1117/12.433863

17 June 2002 Temperature controlled CO₂ laser soldering of pig cornea

Eyal Strassmann M.D., Nino Loya, Dan D. Gaton M.D., Avi Ravid, Noam Kariv, Dov Weinberger M.D., Abraham Katzir

Proceedings Volume 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII; (2002) https://doi.org/10.1117/12.433863
Event: International Symposium on Biomedical Optics, 2002, San Jose, CA, United States

Abstract

Objectives: To determine the feasibility and reproducibility of laser soldering of cornea using biolog ical solder and a fiberopitc temperature conrolled CO2 laser system. Methods: We developed a system based on IR fiber delivery of CO2 laser radiation, for heating a spot on tissue, a fiberoptic radiometer for non-tactile infrared thermometry of the heated spot, and a computer control of the temperature of the spot.Experiments were performed in vivo in 8 corneas of 12Kg piglets eyes, which had 180°, 6mm diameter corneal trephnation perforating cuts.Soldering was done on some of the cuts at a set temperature of 65°C, with adjuvant 47% albumin solder, and standard suturing was done on other cuts, as control.Macroscopic and histologic evaluation was then carried out. Results: On macroscopic examination, the corneas were centrally clear, with corneal neovascularisation only around the sutures.Histologic examination of piglets corneas one week, one month, two months and five months after soldering revealed stromal lamellae which were organized with a fewer inflammatory reaction, in contrast to marked inflammatory response in the suture controls. Conclusions: The laser soldering technology appears to be reliable for closure of large corneal perforating cuts, and may overcome some of the technical difficulties and disadvantages of conventional corneal suture technique.

Citation Download Citation

Eyal Strassmann M.D., Nino Loya, Dan D. Gaton M.D., Avi Ravid, Noam Kariv, Dov Weinberger M.D., and Abraham Katzir "Temperature controlled CO₂ laser soldering of pig cornea", Proc. SPIE 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII, (17 June 2002); https://doi.org/10.1117/12.433863

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available