Paper
14 February 2007 Impact of surface roughness on the sensitivity enhancement of a nanowire-based surface plasmon resonance biosensor
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Abstract
In this study, we investigated the impact of surface roughness on the sensitivity of conventional and nanowire-based surface plasmon resonance (SPR) biosensors. The theoretical research was conducted using rigorous coupled-wave analysis with Gaussian surface profiles of gold films determined by atomic force microscopy. The results suggest that, when surface roughness ranges 1 nm, the sensitivity of a conventional SPR system is not significantly affected regardless of the correlation length. For a nanowire-based SPR biosensor, however, we found that the sensitivity degrades substantially with a decreasing correlation length. Particularly, at a correlation length smaller than 100 nm, random rough surface may induce destructive coupling between excited localized surface plasmons, which can lead to prominent reduction of sensitivity enhancement.
© (2007) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Kyung Min Byun, Soon Joon Yoon, Donghyun Kim, and Sung June Kim "Impact of surface roughness on the sensitivity enhancement of a nanowire-based surface plasmon resonance biosensor", Proc. SPIE 6450, Plasmonics in Biology and Medicine IV, 64500P (14 February 2007); https://doi.org/10.1117/12.699949
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KEYWORDS
Gold

Nanowires

Biosensors

Surface roughness

Surface plasmons

Nanostructures

Thin films

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