Coronary CT angiography: IVUS image fusion for quantitative plaque and stenosis analyses

Henk A. Marquering; Jouke Dijkstra; Quentin J. A. Besnehard; Julien P. M. Duthé; Joanne D. Schuijf; Jeroen J. Bax; Johan H. C. Reiber

doi:10.1117/12.772582

17 March 2008 Coronary CT angiography: IVUS image fusion for quantitative plaque and stenosis analyses

Henk A. Marquering, Jouke Dijkstra, Quentin J. A. Besnehard, Julien P. M. Duthé, Joanne D. Schuijf, Jeroen J. Bax, Johan H. C. Reiber

Author Affiliations +

Proceedings Volume 6918, Medical Imaging 2008: Visualization, Image-Guided Procedures, and Modeling; 69181G (2008) https://doi.org/10.1117/12.772582
Event: Medical Imaging, 2008, San Diego, California, United States

Abstract

Rationale and Objective: Due to the limited temporal and spatial resolution, coronary CT angiographic image quality is not optimal for robust and accurate stenosis quantification, and plaque differentiation and quantification. By combining the high-resolution IVUS images with CT images, a detailed representation of the coronary arteries can be provided in the CT images. Methods: The two vessel data sets are matched using three steps. First, vessel segments are matched using anatomical landmarks. Second, the landmarks are aligned in cross-sectional vessel images. Third, the semi-automatically detected IVUS lumen contours are matched to the CTA data, using manual interaction and automatic registration methods. Results: The IVUS-CTA fusion tool facilitates the unique combined view of the high-resolution IVUS segmentation of the outer vessel wall and lumen-intima transitions on the CT images. The cylindrical projection of the CMPR image decreases the analysis time with 50 percent. The automatic registration of the cross-vessel views decreases the analyses time with 85 percent. Conclusions: The fusion of IVUS images and their segmentation results with coronary CT angiographic images provide a detailed view of the lumen and vessel wall of coronary arteries. The automatic fusion tool makes such a registration feasible for the development and validation of analysis tools.

Citation Download Citation

Henk A. Marquering, Jouke Dijkstra, Quentin J. A. Besnehard, Julien P. M. Duthé, Joanne D. Schuijf, Jeroen J. Bax, and Johan H. C. Reiber "Coronary CT angiography: IVUS image fusion for quantitative plaque and stenosis analyses", Proc. SPIE 6918, Medical Imaging 2008: Visualization, Image-Guided Procedures, and Modeling, 69181G (17 March 2008); https://doi.org/10.1117/12.772582

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