Knowledge discovery in ophthalmology: analysis of wet form of age-related macular degeneration treatment outcomes

Magdalena Ulińska; Emanuel Tataj; Jan J. Mulawka; Jerzy Szaflik

doi:10.1117/12.838221

5 August 2009 Knowledge discovery in ophthalmology: analysis of wet form of age-related macular degeneration treatment outcomes

Magdalena Ulińska, Emanuel Tataj, Jan J. Mulawka, Jerzy Szaflik

Author Affiliations +

Proceedings Volume 7502, Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2009; 75022H (2009) https://doi.org/10.1117/12.838221
Event: Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2009, 2009, Wilga, Poland

Abstract

Age-related Macular Degeneration (AMD), according to epidemiological data, is a main reason of social blindness among elderly people in developed countries. There are two forms of AMD: dry and wet. The first one is of good prognosis with low possibility of serious visual deterioration, while the second one usually leads to quick and severe visual impairment. The aim of our investigations is to analyse results of so called real-life treatment of wet AMD. We analysed outcomes of our patients treated with intravitreal injections of anti-VEGF drugs: Lucentis (61 patients) and Avastin (78 patients). We analysed changes in visual acuity (functional effect) and central retinal thickness (anatomic effect). Both drugs occurred to be efficient in treatment of wet form of AMD, however results were more satisfying in patients with better baseline visual acuity. In our approach we used R environment - an integrated suite of software facilities for data analysis and graphics.

Citation Download Citation

Magdalena Ulińska, Emanuel Tataj, Jan J. Mulawka, and Jerzy Szaflik "Knowledge discovery in ophthalmology: analysis of wet form of age-related macular degeneration treatment outcomes", Proc. SPIE 7502, Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments 2009, 75022H (5 August 2009); https://doi.org/10.1117/12.838221

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available