Detection of biochemical reactions by a surface plasmon resonance senor based on polarization interferometry and angle modulation

Zhaoxu Hu; Xinyuan Chong; Suihua Ma; Yao Li; Yonghong He; Jihua Guo

doi:10.1117/12.843495

28 October 2009 Detection of biochemical reactions by a surface plasmon resonance senor based on polarization interferometry and angle modulation

Zhaoxu Hu, Xinyuan Chong, Suihua Ma, Yao Li, Yonghong He, Jihua Guo

Author Affiliations +

Proceedings Volume 7519, Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009); 75190E (2009) https://doi.org/10.1117/12.843495
Event: Photonics and Optoelectronics Meetings 2009, 2009, Wuhan, China

Abstract

A surface plasmon resonance (SPR) bio-sensing system has been developed. The system is based on polarization interferometry and angel modulation. In this paper, we apply it in the biological detection. We use the DNA fragment of Escherichia coli (Bacterial 16S rDNA universal primer) as bioprobe and . The process that analyte attach with the bioprobe, and coli DNA as analyte, get a resolution about 2.7× 10^-6RI and 0.18nM/L in coli DNA detection.

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Zhaoxu Hu, Xinyuan Chong, Suihua Ma, Yao Li, Yonghong He, and Jihua Guo "Detection of biochemical reactions by a surface plasmon resonance senor based on polarization interferometry and angle modulation", Proc. SPIE 7519, Eighth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2009), 75190E (28 October 2009); https://doi.org/10.1117/12.843495

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KEYWORDS

Surface plasmons

Sensors

Interferometry

Angle modulation

Polarization

Gold

Modulation

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