How to determine detection performance of a DPC-CT
system from a conventional cone beam CT system?

Ke Li; John Garrett; Nicholas Bevins; Joseph Zambelli; Guang-Hong Chen

doi:10.1117/12.2008087

19 March 2013 How to determine detection performance of a DPC-CT system from a conventional cone beam CT system?

Ke Li, John Garrett, Nicholas Bevins, Joseph Zambelli, Guang-Hong Chen

Proceedings Volume 8668, Medical Imaging 2013: Physics of Medical Imaging; 866811 (2013) https://doi.org/10.1117/12.2008087
Event: SPIE Medical Imaging, 2013, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

Although the relative ease of implementation and compact nature of grating-based differential phase contrast CT (DPC-CT) has sparked tremendous enthusiasm for potential medical applications, the pros and cons of this imaging method remains to be addressed before an actual clinical system can be constructed. To address these unknowns, either numerical simulations or direct hardware implementations can be used. However, both approaches have their limitations. It is highly desirable to develop a research method to enable imaging performance prediction for a future DPC-CT system from the performance of an available absorption CT (ACT) system. In this paper, a theoretical framework was developed to accurately predict the noise properties and detection performance of DPC-CT from that of conventional ACT. The framework was derived based on a fundamental noise relationship between DPC-CT and ACT and was experimentally validated. An example has been given in the paper on how the framework can be utilized to predict model observer detectability index of a DPC breast CT constructed based on an existing absorption breast CT. This framework is expected to become a valuable tool in addressing the following questions: (i) With a fixed radiation dose in a particular clinical application, how well can a specific detection/discrimination imaging task can be performed provided that an existing ACT scanner is modified into a DPC-CT by inserting a grating interferometer, which is characterized by a few design parameters (e.g., pitches and duty cycles of the gratings, relative distance between the gratings, etc.) into the ACT system? (ii) If a DPC-CT system can outperform an ACT for certain detection/discrimination tasks under the constraint of identical radiation dose to the image object, how would one optimize design parameters of the gratings in order to maximize its potential clinical benefits?

Citation Download Citation

Ke Li, John Garrett, Nicholas Bevins, Joseph Zambelli, and Guang-Hong Chen "How to determine detection performance of a DPC-CT system from a conventional cone beam CT system?", Proc. SPIE 8668, Medical Imaging 2013: Physics of Medical Imaging, 866811 (19 March 2013); https://doi.org/10.1117/12.2008087

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available