Fabrication of a label-free plasmon immunosensor based on triangular silver nanoplates

Peipei Dong; Yuanyuan Lin; Junwei Di

doi:10.1117/12.2031438

9 August 2013 Fabrication of a label-free plasmon immunosensor based on triangular silver nanoplates

Peipei Dong, Yuanyuan Lin, Junwei Di

Proceedings Volume 8793, Fourth International Conference on Smart Materials and Nanotechnology in Engineering; 87930P (2013) https://doi.org/10.1117/12.2031438
Event: Fourth International Conference on Smart Materials and Nanotechnology in Engineering, 2013, Gold Coast, Australia

Abstract

In this work, we have firstly electrodeposited small gold seeds (average diameter of ~40 nm) onto transparent indium tin oxide (ITO) thin film coated glass. Then silver triangular nanoplates with edge lengths of ~200 nm were fabricated using seed-mediated growth method. The localized surface plasmon resonance (LSPR) peak was located at ~700 nm. Finally, a label-free plasmon immunosensor was prepared by directly immobilizing goat anti-mouse IgG onto silver surface. The performance of the LSPR immunosensor was investigated. The red-shift of the biosensor was linearly proportional to mouse IgG concentration ranged from 5 ng/mL to 500 ng/mL, with a detection limit of 2 ng/mL. The label-free immunosensor was simple, sensitive and selective.

Citation Download Citation

Peipei Dong, Yuanyuan Lin, and Junwei Di "Fabrication of a label-free plasmon immunosensor based on triangular silver nanoplates", Proc. SPIE 8793, Fourth International Conference on Smart Materials and Nanotechnology in Engineering, 87930P (9 August 2013); https://doi.org/10.1117/12.2031438

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