A feasibility study of carotid elastography for risk assessment of atherosclerotic plaques validated by magnetic resonance imaging

Xiaochang Pan; Lingyun Huang; Manwei Huang; Xihai Zhao; Le He; Chun Yuan; Jing Bai; Jianwen Luo

doi:10.1117/12.2042756

20 March 2014 A feasibility study of carotid elastography for risk assessment of atherosclerotic plaques validated by magnetic resonance imaging

Xiaochang Pan, Lingyun Huang, Manwei Huang, Xihai Zhao, Le He, Chun Yuan, Jing Bai, Jianwen Luo

Author Affiliations +

Proceedings Volume 9040, Medical Imaging 2014: Ultrasonic Imaging and Tomography; 904002 (2014) https://doi.org/10.1117/12.2042756
Event: SPIE Medical Imaging, 2014, San Diego, California, United States

Abstract

Stroke is a leading cause of mortality worldwide. One of its main reasons is rupture of carotid atherosclerotic plaques. Conventional B-mode ultrasound images and Doppler/color flow measurements are mostly used to evaluate degree of stenosis, which underestimates plaque vulnerability. Alternatively, the correspondence between multi-contrast magnetic resonance imaging (MRI) features, plaque composition and histology has been well established. In this study, the feasibility of ultrasound carotid elastography in risk assessment of carotid atherosclerotic plaques is investigated. Preliminarily in-vivo results on a small number of human subjects are initially validated by multi-contrast, highresolution MRI, and it shows that maximum strain rate might be feasible to evaluate the plaque vulnerability.

Citation Download Citation

Xiaochang Pan, Lingyun Huang, Manwei Huang, Xihai Zhao, Le He, Chun Yuan, Jing Bai, and Jianwen Luo "A feasibility study of carotid elastography for risk assessment of atherosclerotic plaques validated by magnetic resonance imaging", Proc. SPIE 9040, Medical Imaging 2014: Ultrasonic Imaging and Tomography, 904002 (20 March 2014); https://doi.org/10.1117/12.2042756

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