Direct laser interference patterning (DLIP) technique applied to the development of optical biosensors based on biophotonic sensing cells (bicells)

F. J. Sanza; D. Langheinrich; Jana Berger; A. L. Hernandez; S. Dani; R. Casquel; A. Lavin; A. Otón; Betxu Santamaría; M. Laguna; A. F. Lasagni; M. Holgado.

doi:10.1117/12.2077292

12 March 2015 Direct laser interference patterning (DLIP) technique applied to the development of optical biosensors based on biophotonic sensing cells (bicells)

F. J. Sanza, D. Langheinrich, Jana Berger, A. L. Hernandez, S. Dani, R. Casquel, A. Lavin, A. Otón, Betxu Santamaría, M. Laguna, A. F. Lasagni , M. Holgado.

Author Affiliations +

Proceedings Volume 9351, Laser-based Micro- and Nanoprocessing IX; 935114 (2015) https://doi.org/10.1117/12.2077292
Event: SPIE LASE, 2015, San Francisco, California, United States

Abstract

Direct Laser Interference Patterning (DLIP) technique were employed in the development of optical biosensors based on Biophotonic Sensing Cells (BICELLs). Fabrication was carried out by laser patterning of cross-linked SU-8 thin films deposited both on silicon (Si) and glass substrates. Different photonic structures were developed in order to prove their biosensing suitability by mean of and indirect immunoassay of Bovine Serum Albumin (BSA)/anti-BSA, demonstrating that patterned areas improve the sensitivity in comparison with non-patterned sensing surfaces.

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F. J. Sanza, D. Langheinrich, Jana Berger, A. L. Hernandez, S. Dani, R. Casquel, A. Lavin, A. Otón, Betxu Santamaría, M. Laguna, A. F. Lasagni , and M. Holgado. "Direct laser interference patterning (DLIP) technique applied to the development of optical biosensors based on biophotonic sensing cells (bicells)", Proc. SPIE 9351, Laser-based Micro- and Nanoprocessing IX, 935114 (12 March 2015); https://doi.org/10.1117/12.2077292

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