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Rapid and inexpensive virus detection and quantification at the point-of-care is of paramount importance for HIV management in resource-limited settings. Here, we report on an easy-to-fabricate, cellulose paper-based microchip with printed graphene-modified electrodes for rapid detection of HIV-1 through electrical sensing. We evaluated the effect of electrode material and geometry on the performance of the microchip to detect serially diluted, electrically conductive samples. We evaluated the optimized microchip with HIVspiked samples.
Mohammadali Safavieh,Sultan Khetani,Vivasvat Kaul,Daniel R. Kuritzkes, andHadi Shafiee
"A graphene-modified cellulose paper microchip for HIV detection", Proc. SPIE 9490, Advances in Global Health through Sensing Technologies 2015, 94900G (13 May 2015); https://doi.org/10.1117/12.2183217
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Mohammadali Safavieh, Sultan Khetani, Vivasvat Kaul, Daniel R. Kuritzkes, Hadi Shafiee, "A graphene-modified cellulose paper microchip for HIV detection," Proc. SPIE 9490, Advances in Global Health through Sensing Technologies 2015, 94900G (13 May 2015); https://doi.org/10.1117/12.2183217