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OCT angiography (OCTA) is an extension of optical coherence tomography (OCT) that identifies motion contrast from moving red blood cells to map retinal vasculature in vivo. We propose to use robotically-aligned optical coherence tomography (RAOCT) to acquire OCTA data at multiple illumination angles on the retina in order to reduce shadowing artifacts and enhance vessel visualization. Using RAOCT, retinal volumes were automatically acquired from consented subjects at various pupil entry positions and processed to generate en face OCTA images. These OCTA images were compared to identify areas of changed visualization and reduced shadowing artifact when varying illumination angle.
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Amit Narawane, Mark Draelos, Pablo Ortiz, Ryan P. McNabb, Anthony N. Kuo, Joseph A. Izatt, "Robotically-aligned optical coherence tomography angiography with multiple illumination angles for enhanced vessel visualization," Proc. SPIE PC12360, Ophthalmic Technologies XXXIII, PC123600J (17 March 2023); https://doi.org/10.1117/12.2649505