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17 March 2023 SS-OCT images of the human crystalline lens reveal local changes in the morphology and transparency with ageing
Ashish Gupta, Daniel Ruminski, Alfonso Jiménez Villar, Raul Duarte Toledo, Grzegorz Gondek, Spozmai Panezai, Pablo Artal, Ireneusz P. Grulkowski
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Proceedings Volume PC12360, Ophthalmic Technologies XXXIII; PC123600R (2023) https://doi.org/10.1117/12.2650378
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
The Oxford nomenclature was developed to distinguish the type of cataract based on the optical signal discontinuity (OSD) zones. The OSD zones were used to distinguish sections within the crystalline lens in our study using OCT images. A swept-source OCT was used to observe in-vivo age-related changes in the crystalline lens from the 50 healthy eyes with the age range of 9 to 78 years. The C3 layer (from oxford nomenclature) of the cortex was identified as the section of the crystalline that contributes highly to the age-related changes. We compared age-related degradation of the optical quality of the crystalline lens measurements using commercial VAO and OQAS systems with a custom-built SS-OCT system.
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Ashish Gupta, Daniel Ruminski, Alfonso Jiménez Villar, Raul Duarte Toledo, Grzegorz Gondek, Spozmai Panezai, Pablo Artal, and Ireneusz P. Grulkowski "SS-OCT images of the human crystalline lens reveal local changes in the morphology and transparency with ageing", Proc. SPIE PC12360, Ophthalmic Technologies XXXIII, PC123600R (17 March 2023); https://doi.org/10.1117/12.2650378
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KEYWORDS
Crystals
Optical coherence tomography
Transparency
On-screen displays
Visual optics
Nomenclature
Optical transfer functions
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