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The spatial resolution limit in photoacoustic/thermal imaging is derived from the irreversibility of attenuation of the pressure wave and of heat diffusion during propagation of the signals from the imaged subsurface structures to the sample surface, respectively. The acoustic or temperature signals are converted into so-called virtual waves, which are their reversible counterparts, and which can be used for image reconstruction by well-known ultrasound reconstruction methods, which is an ill-posed inverse problem. The resolution from entropy production is equal to the diffraction limit -which is noise limited. Incorporating sparsity and non-negativity in iterative regularization methods gives a significant resolution enhancement.
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Peter Burgholzer, Gregor Thummerer, Guenther Mayr, "Noise limited spatial resolution in photoacoustic reconstructions from photothermal measurements," Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123792D (27 March 2023); https://doi.org/10.1117/12.2655364