Dielectric nano-interfaces for biosensing and cell mechanobiology studies (Conference Presentation)

Hao Wang; Taerin Chung; Haogang Cai

doi:10.1117/12.2650444

16 March 2023 Dielectric nano-interfaces for biosensing and cell mechanobiology studies (Conference Presentation)

Hao Wang, Taerin Chung, Haogang Cai

Proceedings Volume PC12394, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XX; PC1239402 (2023) https://doi.org/10.1117/12.2650444
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

We developed novel dielectric nano-interfaces for biomedical applications. For biosensing, TiO2 metasurfaces avoids the damping loss and heating problems intrinsic to plasmonic sensors. In addition to conventional spectral shift, the imaging-based and colorimetric readouts sidestep the requirements for spectrometer or hyperspectral imaging. By working in the visible spectrum, TiO2 metasurfaces point towards ultra-compact, cost-effective, and eye-perceptible solutions for point-of-care testing. For cell mechanobiology study, TiO2 nanopatterns have minimal fluorescence interference, which are compatible with super-resolution microscopy, and thereby enable mechanistic dissection of molecular-scale signaling events, in conjunction with nanoscale manipulation of important transmembrane receptors in mechanobiology studies.

Conference Presentation

Citation Download Citation

Hao Wang, Taerin Chung, and Haogang Cai "Dielectric nano-interfaces for biosensing and cell mechanobiology studies (Conference Presentation)", Proc. SPIE PC12394, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XX, PC1239402 (16 March 2023); https://doi.org/10.1117/12.2650444

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