Multiplexing molecular spectroscopy via metasurface using plasmonic resonance energy transfer

Hongyoon Kim; Inki Kim; Seungyeon Han; Joohoon Kim; Yangkyu Kim; Inhee Choi; Junsuk Rho; Luke P. Lee

doi:10.1117/12.2647810

17 March 2023 Multiplexing molecular spectroscopy via metasurface using plasmonic resonance energy transfer

Hongyoon Kim, Inki Kim, Seungyeon Han, Joohoon Kim, Yangkyu Kim, Inhee Choi, Junsuk Rho, Luke P. Lee

Proceedings Volume PC12432, High Contrast Metastructures XII; PC124320L (2023) https://doi.org/10.1117/12.2647810
Event: SPIE OPTO, 2023, San Francisco, California, United States

Abstract

Plasmonic resonance energy transfer (PRET) based imaging has been proposed as an effective label-free real-time biomolecular absorption spectroscopic method that enables the detection of biomolecules and dynamic cell activities. Here, we present a metasurface-based PRET-imaging platform that effectively engineers the darkfield scattering spectrum using the gap plasmon and grating effect. As a demonstration, three different biomolecules (Cyt c, Chl a, Chl b) are simultaneously detected using our metasurface-based PRET-imaging platform. Our proposed metasurface-based PRET-imaging platform enables continuous monitoring in the spatial region and multiplexed PRET sensing of multiple biomolecules with different absorption spectrums in the visible.

Conference Presentation

Citation Download Citation

Hongyoon Kim, Inki Kim, Seungyeon Han, Joohoon Kim, Yangkyu Kim, Inhee Choi, Junsuk Rho, and Luke P. Lee "Multiplexing molecular spectroscopy via metasurface using plasmonic resonance energy transfer", Proc. SPIE PC12432, High Contrast Metastructures XII, PC124320L (17 March 2023); https://doi.org/10.1117/12.2647810

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