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Precise manufacturing of volume scattering phantoms with direct control of the scattering and absorption coefficients opens up the possibility to examine the behavior of focus generation and the resulting enhancement behind these phantoms by applying wavefront shaping. Volume scattering phantoms allow measurements on samples with selected optical thicknesses. Specific combinations of scattering and absorption properties can mimic the interaction of coherent monochromatic light with biological tissue at a predetermined wavelength. Phantoms similar to muscle and fat tissue and solely scattering samples are being designed to characterize the achievable enhancement of the optimized focus intensity versus the mean intensity before optimization.
Niklas Fritzsche,Felix Ott,Karsten Pink, andAlwin Kienle
"Focusing coherent light through volume scattering phantoms with well defined optical properties via wavefront shaping", Proc. SPIE PC12622, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials VI, PC126220V (10 August 2023); https://doi.org/10.1117/12.2673180
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Niklas Fritzsche, Felix Ott, Karsten Pink, Alwin Kienle, "Focusing coherent light through volume scattering phantoms with well defined optical properties via wavefront shaping," Proc. SPIE PC12622, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials VI, PC126220V (10 August 2023); https://doi.org/10.1117/12.2673180