Boris Majaron is a senior staff member (Scientific Advisor) at Jožef Stefan Institute, Department of Complex Matter, and Professor of Physics at University of Ljubljana, Slovenia. He has obtained his M.S. degree in Solid-State Physics with Electrooptics and Ph.D. degree in Physics from University of Ljubljana and postdoctoral training at Beckman Laser Institute at University of California at Irvine, USA.
After beeing trained in optical spectroscopy of solid-state laser materials and laser physics, his research focus drfited to biophotonics and laser surgery. Within the later he has studied thermomechanical ablation of hard and soft biological tissues, and laser treatments in dermatology. He was recently involved in noninvasive characterization and imaging of skin using optical spectroscopy and/or photothermal radiometry combined with numerical modeling, and development of micro- and nanostructures for bioimaging and sensing. He has served on Editorial Boards of several scientific journals and Committees of international conferences.
After beeing trained in optical spectroscopy of solid-state laser materials and laser physics, his research focus drfited to biophotonics and laser surgery. Within the later he has studied thermomechanical ablation of hard and soft biological tissues, and laser treatments in dermatology. He was recently involved in noninvasive characterization and imaging of skin using optical spectroscopy and/or photothermal radiometry combined with numerical modeling, and development of micro- and nanostructures for bioimaging and sensing. He has served on Editorial Boards of several scientific journals and Committees of international conferences.
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In present study we evaluate the potential of this approach for quantitative evaluation of tattoos. For this purpose, we apply a three-layer optical model of skin consisting of epidermis, upper dermis, and bottom dermis which includes the tattoo ink. The study involves healthy volunteer with black tattoo undergoing tattoo removal treatment with Q-switched Nd:YAG laser. The measurements are performed in four tattoo sites and one nearby healthy site before and after laser removal treatment. The results indicate the depth of tattoo, amount of tattoo ink and scattering properties in the dermis. This information can be used to improve our understanding of laser tattoo removal procedure.
This report involves two human volunteers with bruises acquired incidentally at a known time point. DRS spectra in visible spectral range are obtained from laterally uniform lesion sites using an integrating sphere. PPTR measurements involve irradiation with a millisecond laser pulse at 532 nm and recording the resulting transient change of mid-infrared emission with a fast infrared camera. Data from both measurements are analyzed simultaneously by fitting with predictions from a dedicated numerical simulation of light and heat transport in a multi-layer model of human skin. The results show a prominent increase of the dermal hemoglobin content and reduction of its oxygenation level relative to a nearby intact site (resulting from blood extravasation), followed by a rise of the bilirubin content. The parameters of a simple dynamical model of a self-healing bruise are then assessed by fitting together a set of experimental data acquired at different times post injury. The results indicate a rise and subsequent decrease of the hemoglobin decomposition rate, as the inflammatory response first kicks in and then gradually subsides.
Computational model to evaluate port wine stain depth profiling using pulsed photothermal radiometry
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