The structural-logical diagram and research design by the methods of polarization-phase tomography of linear dichroism of the polycrystalline structure [1-5] of histological sections of the brain are presented. Differential diagnosis of the formation of hemorrhages of traumatic genesis, cerebral infarction of ischemic and hemorrhagic genesis by the method of differential Mueller-matrix mapping of amplitude anisotropy - linear dichroism maps (ALD) of histological brain sections and operational characteristics of the method of their statistical analysis. Differential diagnosis of the prescription of the formation of hemorrhages of traumatic genesis, cerebral infarction, ischemic and hemorrhagic genesis by the method of differential Mueller-matrix mapping of amplitude anisotropy - temporal dynamics of changes in the statistical structure of ALD maps of histological brain sections.
The paper presents the results of the possibility of a polarization-interference approach to the analysis of microscopic images polycrystalline blood films of patients of benign and malignant prostate tumours with different degrees of differentiation. Measurements and analysis of maps and histograms of the distribution of the local contrast value of polarization-interference distributions of microscopic images of polycrystalline blood films of patients . Determination of the relationship between the statistical moments of the 1st - 4th orders characterizing the distributions of the local contrast value of the polarization-interference distributions of microscopic images of polycrystalline blood films of patients. Determination of statistical criteria for polarization-interference diagnosis of histological sections of biopsy of adenoma and adenocarcinoma with varying degrees of differentiation. Determination of sensitivity, specificity, accuracy of the polarization interferometry method for differential diagnosis of polycrystalline blood films of patients of adenoma and adenocarcinoma with varying degrees of differentiation.
A new digital technique of objective differential diagnosis of the septic process severity was developed and tested experimentally by polarization-phase mapping of microscopic images of histological sections of the liver of laboratory rats based on statistical and information analysis of phase shift distributions.
A theoretical basis for the method of polarization-phase mapping of optically thin polycrystalline films of human biological fluids is given. The coordinate distributions of the magnitude of the phase shifts and the polarization-inhomogeneous microscopic images of polycrystalline films of the synovial fluid of the human joint are investigated. In the framework of the statistical (statistical moments of 1st-4th order), correlation (dispersion and kurtosis characterizing autocorrelation functions) and fractal (dispersion, characterizing the logarithmic dependencies of power spectra) approaches, objective criteria for the distribution of local contrast values are established. The possibility of differentiation of weak changes in the optical anisotropy of synovial fluid films in patients with different severity of the pathology of the knee joint has been determined. Comparative studies of the accuracy of this method and the traditional method of polarization mapping.
The optical model of polycrystalline networks of human skin is suggested. The results of investigation of the values of
statistical (statistical moments of the 1st-4th order) parameters of polarization inhomogeneous images of skin surface in
Fourier domain are presented. The diagnostic criteria of pathological process in human skin and its severity degree
differentiation are determined.
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