Dr. Nisan Ozana Profile

Dr. Nisan Ozana

at Bar Ilan Univ

SPIE Involvement:

Editorial Board Member: Neurophotonics | Author

Publications (25)

Proceedings Article | 20 June 2024 Presentation + Paper

Rolling-shutter laser speckle analysis in bio-photonics

Sammy Apsel, Vika Tarle, Michal Yemini, Zeev Zalevsky, Nisan Ozana

Proceedings Volume 13006, 130060U (2024) https://doi.org/10.1117/12.3001702

KEYWORDS: Cameras, Speckle pattern, Sampling rates, Lung, Camera shutters, Vibration, Speckle analysis, Signal detection, Video, Light sources and illumination

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SPIE Journal Paper | 6 September 2023 Open Access

Enhancing diffuse correlation spectroscopy pulsatile cerebral blood flow signal with near-infrared spectroscopy photoplethysmography

Kuan Cheng Wu, Alyssa Martin, Marco Renna, Mitchell Robinson, Nisan Ozana, Stefan A. Carp, Maria Angela Franceschini

NPh, Vol. 10, Issue 03, 035008, (September 2023) https://doi.org/10.1117/12.10.1117/1.NPh.10.3.035008

KEYWORDS: Near infrared spectroscopy, Signal to noise ratio, Cerebral blood flow, Blood circulation, Spectroscopy, Blood, Oxygenation, Neurophotonics, Resistance, Sampling rates

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Proceedings Article | 17 March 2023 Presentation

Optical noninvasive resting-state identification of ∆9-tetrahydrocannabinol (THC)

Nisan Ozana, Michael Pascale, Kevin Potter, Brian Kendzior, Gladys Pachas, Eden Evins, Jodi Gilman

Proceedings Volume PC12365, PC1236508 (2023) https://doi.org/10.1117/12.2650575

KEYWORDS: Machine learning, Safety, Prefrontal cortex

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Proceedings Article | 7 March 2023 Presentation

Multistate time-multiplexed system for functional time-domain diffuse correlation spectroscopy with SNSPDs

Marco Renna, Zachary Starkweather, Mitchell Robinson, Nisan Ozana, Alyssa Martin, Stefan Carp, Maria Angela Franceschini

Proceedings Volume PC12376, PC123760D (2023) https://doi.org/10.1117/12.2650215

KEYWORDS: Spectroscopy, Brain, Signal to noise ratio, Blood circulation, Temporal resolution, Superconductors, Spatial resolution, Single photon detectors, Pulsed laser operation, Point spread functions

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Proceedings Article | 30 May 2022 Presentation

A novel 32x32 InP/ InGaAs SPAD array for multi-channel time-gated diffuse correlation spectroscopy

Marco Renna, Jonathan Richardson, George Jordy, Tom Cheng, Eric Ringdahl, Mitchell Robinson, Nisan Ozana, Niyom Lue, Brian Aull, Stefan Carp, Erik Duerr, Maria Angela Franceschini, Megan Blackwell

Proceedings Volume PC12089, PC120890E (2022) https://doi.org/10.1117/12.2619112

KEYWORDS: Indium gallium arsenide, Spectroscopes, Sensors, Photons, Tissue optics, Spectroscopy, Imaging systems, Head, Brain, Single photon detectors

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Proceedings Article | 30 May 2022 Presentation

Monitoring cerebral blood flow with superconducting nanowire detectors

Maria Franceschini, Nisan Ozana, Mitchell Robinson, Megan Blackwell, Stefan Carp, Marco Renna

Proceedings Volume PC12089, PC1208907 (2022) https://doi.org/10.1117/12.2622923

KEYWORDS: Superconductors, Sensors, Nanowires, Cerebral blood flow, Signal to noise ratio, Near infrared spectroscopy, Photon counting, Traumatic brain injury, Spectroscopy, Speckle

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Proceedings Article | 2 March 2022 Presentation

Design and characterization of a multi-channel time-gated diffuse correlation spectroscopy system at 1064nm

Marco Renna, Jonathan Richardson, George Jordy, Tom Cheng, Mitchell Robinson, Nisan Ozana, Dibbyan Mazumder, Niyom Lue, Brian Aull, Bernhard Zimmerman, Stefan Carp, Erik Duerr, David Boas, Maria Angela Franceschini, Megan Blackwell

Proceedings Volume PC11959, PC1195908 (2022) https://doi.org/10.1117/12.2610207

KEYWORDS: Spectroscopes, Spectroscopy, Sensors, Photons, Imaging systems, Head, Single photon detectors, Single photon, Sensor performance, Semiconductor lasers

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SPIE Journal Paper | 19 August 2021 Open Access

Superconducting nanowire single-photon sensing of cerebral blood flow

Nisan Ozana, Alexander Zavriyev, Dibbyan Mazumder, Mitchell Robinson, Kutlu Kaya, Megan Blackwell, Stefan Carp, Maria Angela Franceschini

NPh, Vol. 8, Issue 03, 035006, (August 2021) https://doi.org/10.1117/12.10.1117/1.NPh.8.3.035006

KEYWORDS: Signal to noise ratio, Photons, Sensors, Brain, Superconductors, Nanowires, Cerebral blood flow, Blood circulation, Neurophotonics, Modulation

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SPIE Journal Paper | 12 August 2021 Open Access

Optimization of time domain diffuse correlation spectroscopy parameters for measuring brain blood flow

Dibbyan Mazumder, Melissa Wu, Nisan Ozana, Davide Tamborini, Maria Angela Franceschini, Stefan Carp

NPh, Vol. 8, Issue 03, 035005, (August 2021) https://doi.org/10.1117/12.10.1117/1.NPh.8.3.035005

KEYWORDS: Photons, Monte Carlo methods, Picosecond phenomena, Sensors, Head, Tissue optics, Spectroscopy, Brain, Blood circulation, Neurophotonics

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Significance: Time domain diffuse correlation spectroscopy (TD-DCS) can offer increased sensitivity to cerebral hemodynamics and reduced contamination from extracerebral layers by differentiating photons based on their travel time in tissue. We have developed rigorous simulation and evaluation procedures to determine the optimal time gate parameters for monitoring cerebral perfusion considering instrumentation characteristics and realistic measurement noise. Aim: We simulate TD-DCS cerebral perfusion monitoring performance for different instrument response functions (IRFs) in the presence of realistic experimental noise and evaluate metrics of sensitivity to brain blood flow, signal-to-noise ratio (SNR), and ability to reject the influence of extracerebral blood flow across a variety of time gates to determine optimal operating parameters. Approach: Light propagation was modeled on an MRI-derived human head geometry using Monte Carlo simulations for 765- and 1064-nm excitation wavelengths. We use a virtual probe with a source–detector separation of 1 cm placed in the pre-frontal region. Performance metrics described above were evaluated to determine optimal time gate(s) for different IRFs. Validation of simulation noise estimates was done with experiments conducted on an intralipid-based liquid phantom. Results: We find that TD-DCS performance strongly depends on the system IRF. Among Gaussian pulse shapes, ∼300 ps pulse length appears to offer the best performance, at wide gates (500 ps and larger) with start times 400 and 600 ps after the peak of the TPSF at 765 and 1064 nm, respectively, for a 1-s integration time at photon detection rates seen experimentally (600 kcps at 765 nm and 4 Mcps at 1064 nm). Conclusions: Our work shows that optimal time gates satisfy competing requirements for sufficient sensitivity and sufficient SNR. The achievable performance is further impacted by system IRF with ∼300 ps quasi-Gaussian pulse obtained using electro-optic laser shaping providing the best results.

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Proceedings Article | 5 March 2021 Presentation

Time-gated diffuse correlation spectroscopy for functional imaging via 1064 nm pulse laser shaping and superconducting nanowire single photon sensing

Nisan Ozana, Adriano Peruch, Mitchell Robinson, Dibbyan Mazumder, Megan Blackwell, Niyom Lue, Stefan Carp, Maria Angela Franceschini

Proceedings Volume 11629, 116292F (2021) https://doi.org/10.1117/12.2578909

KEYWORDS: Superconductors, Spectroscopy, Pulsed laser operation, Nanowires, Single photon, Photons, Imaging spectroscopy, Functional imaging, Brain, Tissue optics

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Proceedings Article | 5 March 2021 Presentation

Simulation and experimental verification of optimal time domain diffuse correlation spectroscopy (TD-DCS) parameters for measuring brain blood flow

Dibbyan Mazumder, Melissa Wu, Nisan Ozana, Davide Tamborini, Maria Angela Franceschini, Stefan Carp

Proceedings Volume 11641, 116410F (2021) https://doi.org/10.1117/12.2577787

KEYWORDS: Monte Carlo methods, Blood circulation, Spectroscopy, Brain, Tissue optics, Tissues, Geometrical optics, Photons, Optical simulations, Motion measurement

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Proceedings Article | 5 March 2021 Presentation

High framerate, InGaAs camera for interferometric diffuse correlation spectroscopy (iDCS) beyond the water peak

Mitchell Robinson, Stefan Carp, Adriano Peruch, Nisan Ozana, Maria Franceschini

Proceedings Volume 11641, 116410O (2021) https://doi.org/10.1117/12.2578894

KEYWORDS: Spectroscopy, Indium gallium arsenide, Cameras, Sensors, Interferometry, Signal to noise ratio, Scattering, Blood circulation, Tissue optics

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Proceedings Article | 5 March 2021 Presentation

Continuous wave diffuse correlation spectroscopy beyond the water peak enabled by InGaAs SPAD cross correlation

Mitchell Robinson, Stefan Carp, Adriano Peruch, Nisan Ozana, Maria Franceschini

Proceedings Volume 11629, 116291Q (2021) https://doi.org/10.1117/12.2578914

KEYWORDS: Spectroscopy, Indium gallium arsenide, Sensors, Blood circulation, Silicon, Signal to noise ratio, Photons, Standards development, Single photon

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SPIE Journal Paper | 29 September 2020 Open Access

Diffuse correlation spectroscopy measurements of blood flow using 1064 nm light

Stefan Carp, Davide Tamborini, Dibbyan Mazumder, Kuan-Cheng Wu, Mitchell Robinson, Kimberly Stephens, Oleg Shatrovoy, Niyom Lue, Nisan Ozana, Megan Blackwell, Maria Angela Franceschini

JBO, Vol. 25, Issue 09, 097003, (September 2020) https://doi.org/10.1117/12.10.1117/1.JBO.25.9.097003

KEYWORDS: Blood circulation, Absorption, Scattering, Signal to noise ratio, Tissue optics, Near infrared spectroscopy, Spectroscopy, Tissues, Signal attenuation, Sensors

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Proceedings Article | 2 April 2020 Presentation + Paper

Remote thermal sensing of tissues based upon analysis of time-changing back-scattered speckle patterns

Matan Benyamin, Hadar Genish, Ran Califa, Nissan Ozana, Ariel Schwarz, Zeev Zalevsky

Proceedings Volume 11363, 113631E (2020) https://doi.org/10.1117/12.2556227

KEYWORDS: Speckle pattern, Temperature metrology, Tissues, Speckle, Skin, Sensors, Laser scattering, Scattering, Thermal sensing, Biological research

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Proceedings Article | 21 February 2020 Paper

Remote optical sensing of neuronal tissue vibrations during regeneration

Ariel Halevi, Sharon Cohen, Nairous Farah, Asaf Shoval, Orit Shefi, Yossi Mandel, Zeev Zalevsky, Nisan Ozana

Proceedings Volume 11254, 112540I (2020) https://doi.org/10.1117/12.2550119

KEYWORDS: Action potentials, Cameras, Speckle pattern, Nerve, Connective tissue, Optical sensing, Tissue optics, Remote sensing, Laser optics

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Proceedings Article | 22 July 2019 Open Access

Secondary speckle-based tomography and tissue probing (Conference Presentation)

Ariel Schwarz, Nisan Ozana, Ran Califa, Amir Shemer, Hadar Genish, Zeev Zalevsky

Proceedings Volume 11060, 1106006 (2019) https://doi.org/10.1117/12.2524968

KEYWORDS: Tomography, Tissues, Speckle pattern, Laser tissue interaction, Tissue optics, Modulation, Natural surfaces, Laser scattering, Light scattering, Elastography

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Proceedings Article | 7 March 2019 Paper

Speckle based sensing of chemicals by an acoustic excitation in aqueous solutions

Hadar Genish, Nisan Ozana, Zeev Zalevsky

Proceedings Volume 10895, 108950K (2019) https://doi.org/10.1117/12.2511594

KEYWORDS: Acoustics, Glucose, Speckle pattern, Speckle, Modulation, Ferroelectric materials, Chemical analysis, Biological and chemical sensing, Optical activity, Statistical analysis

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Proceedings Article | 27 February 2019 Paper

Bio-sensor based on multiclass support vector machine with a reject option

Stav Buchsbaum, Yossi Keshet, Nisan Ozana, Zeev Zalevsky

Proceedings Volume 10871, 108710O (2019) https://doi.org/10.1117/12.2507428

KEYWORDS: Glucose, Blood, Algorithm development, Biosensors, Biomedical optics, Probability theory, Remote sensing, Image classification, Speckle

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SPIE Journal Paper | 15 November 2018 Open Access

Intraocular pressure remote photonic biomonitoring based on temporally encoded external sound wave stimulation

Aviya Bennett, Yevgeny Beiderman, Sergey Agdarov, Yafim Beiderman, Nisan Ozana, Michael Belkin, Zeev Zalevsky

JBO, Vol. 23, Issue 11, 117001, (November 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.11.117001

KEYWORDS: Eye, Biomedical optics, Cornea, Speckle pattern, Cameras, Eye models, Calibration, Speckle, Acoustics, Signal to noise ratio

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SPIE Journal Paper | 17 August 2017

Nanostructures with periodic heating–cooling cycles for photoacoustic imaging using continuous-wave illumination

Yossef Danan, Dror Malka, Nisan Ozana, Zeev Zalevsky

JNP, Vol. 12, Issue 01, 012507, (August 2017) https://doi.org/10.1117/12.10.1117/1.JNP.12.012507

KEYWORDS: Nanostructures, Nanoparticles, Nanorods, Photoacoustic imaging, Gold, Absorption, Tissues, Silicon, Continuous wave operation, Silica

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Proceedings Article | 22 February 2017 Paper

Remote optical stethoscope and optomyography sensing device

Mark Golberg, Sagi Polani, Nisan Ozana, Yevgeny Beiderman, Javier Garcia, Joaquin Ruiz-Rivas Onses, Martin Sanz Sabater, Max Shatsky, Zeev Zalevsky

Proceedings Volume 10077, 100771E (2017) https://doi.org/10.1117/12.2253407

KEYWORDS: Remote sensing, Speckle pattern, Glucose, Distance measurement, Biosensing, Photonic devices, In vivo imaging, Motion estimation, Sensors, Heart, Chest, Tissue optics, Laser applications

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SPIE Journal Paper | 2 June 2016 Open Access

Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect

Nisan Ozana, Yevgeny Beiderman, Arun Anand, Bahram Javidi, Sagi Polani, Ariel Schwarz, Amir Shemer, Javier García-Monreal, Zeev Zalevsky

JBO, Vol. 21, Issue 06, 065001, (June 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.6.065001

KEYWORDS: Glucose, Magnetism, Magneto-optics, Magnesium, Speckle pattern, Speckle, Optical sensors, Biomedical optics, Blood, Polarization

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Proceedings Article | 22 April 2016 Presentation + Paper

Non-contact optical sensor for detection of glucose concentration using a magneto-optic effect

Nisan Ozana, Yevgeny Beiderman, Arun Anand, Baharam Javidi, Sagi Polani, Ariel Schwarz, Amir Shemer, Javier García, Zeev Zalevsky

Proceedings Volume 9721, 97210S (2016) https://doi.org/10.1117/12.2211615

KEYWORDS: Glucose, Blood, Magnetism, Magneto-optics, Optical sensors, Speckle, Biosensing, Cameras, Polarization, Wavefronts, Speckle pattern, Water, Acoustics

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Proceedings Article | 29 February 2016 Paper

Remote optical configuration of pigmented lesion detection and diagnosis of bone fractures

Nisan Ozana, Yael Bishitz, Yevgeny Beiderman, Javier Garcia, Zeev Zalevsky, Ariel Schwarz

Proceedings Volume 9689, 968916 (2016) https://doi.org/10.1117/12.2211380

KEYWORDS: Bone, Sensors, Speckle pattern, Blood, Surgery, Speckle, Biosensing, Heart, Glucose, Visualization, Skin, Tissues, Optical testing, Cancer, Diagnostics

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Showing 5 of 25 publications

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