Ms. Serena Q. Z. Shi Profile

Serena Q. Z. Shi

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Publications (3)

Proceedings Article | 3 April 2024 Presentation

Development of an inflatable murine lung phantom for phase-contrast and darkfield imaging

Serena Qinyun Shi, Austin Zhuang, Ryan Fair, Peter Noël

Proceedings Volume 12930, 129300X (2024) https://doi.org/10.1117/12.3005456

KEYWORDS: Lung, Tissues, Biological samples, X-ray imaging, X-rays, Pulmonary disorders, Design and modelling, Visualization, Vacuum, Aorta

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Proceedings Article | 7 April 2023 Presentation + Paper

Multimodal single-shot x-ray phase-contrast imaging using a high-resolution micropillar-based grating

Abdollah Pil-Ali, Serena Qinyun Shi, Sahar Adnani, Peter Noël, Karim Karim

Proceedings Volume 12463, 1246309 (2023) https://doi.org/10.1117/12.2655809

KEYWORDS: X-rays, X-ray imaging, X-ray detectors, Imaging systems, Silicon, Absorption, Particles, Electroplating

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Grating-based X-ray phase-contrast imaging (XPCi) systems offer higher sensitivity compared to other XPCi methods; however, realizing a high-resolution, compact, dose-efficient imaging system has been a significant challenge from technological and practical points of view until now. X-ray gratings quality and characteristics directly determine the final imaging quality, where a proper grating fabrication process can potentially minimize image artifacts and increase the system visibility. To achieve a high-resolution, compact, dose-efficient XPCi system, high-resolution detectors and high-resolution X-ray absorption gratings are a must. Moreover, an efficient image processing method is required to retrieve multimodal XPCi information—transmission, refraction (phase-contrast), and dark-field—efficiently and simultaneously. In this work, we report on a compact XPCi system that enables multimodal information retrieval through single-shot imaging with two-directional sensitivity. We first present an elegant cost-effective fabrication method to make high-resolution micropillar-based X-ray absorption gratings. A prototype 2D grating is fabricated with micropillars with 4 μm in diameter, periodicity of 16.3 μm, and aspect ratio of more than 40. This grating is then employed along with a prototype hybrid a-Se/CMOS direct conversion high-resolution X-ray detector with a pixel pitch of 8 μm in a compact system with a polychromatic microfocus source to perform X-ray phase-contrast imaging of various samples. We successfully demonstrate a single-shot XPCi and retrieve multimodal XPCi data with transmission and dark-field metrics. The final system is a promising candidate for XPCi applications as it facilitates single-shot imaging, which reduces the exposure dose on samples and yields multimodal XPCi images efficiently, all in a compact bench-top setup. The delivered X-ray dose at the sample, resolution of the system, and compactness of the reported imaging setup are potentially beneficial for ex vivo, in vivo, and computed tomography (CT) imaging applications.

Proceedings Article | 4 April 2022 Poster

Displacement retrieval for speckle-based X-ray phase-contrast imaging using a convolutional neural network

Serena Shi, Nadav Shapira, Peter Noël, Sebastian Meyer

Proceedings Volume 12032, 1203225 (2022) https://doi.org/10.1117/12.2608352

KEYWORDS: X-rays, X-ray imaging, Convolutional neural networks, Speckle imaging, Speckle pattern, Speckle, X-ray optics, Modulation, Detection and tracking algorithms, Tissue optics

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