Research Papers: Imaging

Three-dimensional imaging of normal skin and nonmelanoma skin cancer with cellular resolution using Gabor domain optical coherence microscopy

[+] Author Affiliations
Kye-Sung Lee, Huimin Zhao, Natthani Meemon, Laura Khoudeir, Jannick P. Rolland

University of Rochester, The Institute of Optics, 275 Hutchinson Road, Rochester New York 14627

Sherrif F. Ibrahim

University of Rochester Medical Center, Department of Dermatology, 400 Red Creek Drive, Suite 200, Rochester, New York 14623

J. Biomed. Opt. 17(12), 126006 (Dec 03, 2012). doi:10.1117/1.JBO.17.12.126006
History: Received May 30, 2012; Revised October 20, 2012; Accepted October 31, 2012
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Abstract.  We investigate morphological differences in three-dimensional (3-D) images with cellular resolution between nonmelanoma skin cancer and normal skin using Gabor domain optical coherence microscopy. As a result, we show for the first time cellular optical coherence images of 3-D features differentiating cancerous skin from normal skin. In addition, in vivo volumetric images of normal skin from different anatomic locations are shown and compared.

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© 2012 Society of Photo-Optical Instrumentation Engineers

Citation

Kye-Sung Lee ; Huimin Zhao ; Sherrif F. Ibrahim ; Natthani Meemon ; Laura Khoudeir, et al.
"Three-dimensional imaging of normal skin and nonmelanoma skin cancer with cellular resolution using Gabor domain optical coherence microscopy", J. Biomed. Opt. 17(12), 126006 (Dec 03, 2012). ; http://dx.doi.org/10.1117/1.JBO.17.12.126006


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