Optical property measurements in mammalian cartilage

Steen J. Madsen; Eugene A. Chu; Brian Jet-Fei Wong M.D.

doi:10.1117/12.388057

13 June 2000 Optical property measurements in mammalian cartilage

Steen J. Madsen, Eugene A. Chu, Brian Jet-Fei Wong M.D.

Proceedings Volume 3914, Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical; (2000) https://doi.org/10.1117/12.388057
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

The optical properties of porcine nasal cartilage have been determined at a wavelength of 632.8 nm using two different techniques. A single integrating sphere method was used to measure diffuse reflectance and diffuse transmittance, while total attenuation was determined from separate measurements of collimated transmission. Optical properties (absorption and scattering coefficients, and scattering anisotropy) were obtained by comparing measured results with predictions of Monte Carlo computer simulations. An estimate of the validity of the optical properties was obtained by measuring the optical penetration depth in bulk cartilage tissue. The optical properties of porcine nasal cartilage are characterized by low absorption (0.14 plus or minus 0.05 cm^-1) and high scatter (304 plus or minus 47 cm^-1). The scattered light is highly forward peaked as indicated by the mean cosine of the scattering angle (0.973 plus or minus 0.005). Based on these results, the calculated optical penetration depth was in good agreement with that measured in bulk tissue. The results presented here are compared to those obtained in mammalian cartilage tissue by other investigators.

Citation Download Citation

Steen J. Madsen, Eugene A. Chu, and Brian Jet-Fei Wong M.D. "Optical property measurements in mammalian cartilage", Proc. SPIE 3914, Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical, (13 June 2000); https://doi.org/10.1117/12.388057

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