Laser-induced breakdown spectroscopy (LIBS) is applied to investigate the effect of diabetes mellitus (DM) on the elemental composition of fingernails. Measurements are carried out on 85 fingernail clippings including 51 diabetic and 34 control subjects. An auto-focus system has been designed and used in experiments to improve the repeatability of LIBS measurements. Classification of diabetic and nondiabetic subjects is examined using discriminant function analysis (DFA) method. This classification is based on 82 atomic, ionic, and molecular emission lines belonging to 13 elements as well as one molecule of fingernails. Emission lines that can be used as the best predictors are identified. The possibility of using this method for screening purposes is discussed based on the classification results. This preliminary work shows the ability of LIBS of fingernails in discrimination of DM patients and nondiabetic subjects using DFA method and its feasibility in screening purposes.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.