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3D printed reference targets with ICG-matching spectral characteristics allow for characterization and performance monitoring of fluorescence-guided surgery (FGS) systems. The developed 3D printing methodology allowed for manufacturing of standardized geometrical shapes and anatomical mimicking structures to test the concentration sensitivity, depth sensitivity, fluorescence resolution, and signal detail characteristics of FGS systems. Incorporation of various fluorophores and tuning of the optical properties of the 3D printed materials enables production of application-specific targets that can help develop new indications and provide characterization tools for novel imaging systems.
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Alberto J. Ruiz, Ethan P. M. LaRochelle, Brian W. Pogue, "3D printed targets for fluorescence guided surgery systems," Proc. SPIE PC11951, Design and Quality for Biomedical Technologies XV, PC1195105 (7 March 2022); https://doi.org/10.1117/12.2613766