Time-gated diffuse correlation spectroscopy system at 1064nm using superconducting nanowire single photon detectors for monitoring of traumatic brain injury

Ulas Sunar

doi:10.1117/12.2663934

15 June 2023 Time-gated diffuse correlation spectroscopy system at 1064nm using superconducting nanowire single photon detectors for monitoring of traumatic brain injury

Ulas Sunar

Author Affiliations +

Proceedings Volume PC12512, Advanced Photon Counting Techniques XVII; PC1251207 (2023) https://doi.org/10.1117/12.2663934
Event: SPIE Defense + Commercial Sensing, 2023, Orlando, Florida, United States

Abstract

Time-gated diffuse correlation spectroscopy (TG-DCS) was used in neuro-intensive care settings for monitoring of patients with severe traumatic brain injury. Here, I will present recent results of clinical translation of TG-DCS at the neuro-intensive care unit by implementing measurements at 1064 nm due to high sensitivity of superconducting nanowire single photon detectors. We obtained a significant correlation (ρ = 0.76) between TG-DCS and invasive thermal diffusion flowmetry. We also demonstrate high temporal resolution to obtain pulsatile flow measurements. Overall, the results demonstrate the first clinical translation capability of the TG-DCS system at 1064 nm using a superconducting nanowire single-photon detector.

Conference Presentation

Citation Download Citation

Ulas Sunar "Time-gated diffuse correlation spectroscopy system at 1064nm using superconducting nanowire single photon detectors for monitoring of traumatic brain injury", Proc. SPIE PC12512, Advanced Photon Counting Techniques XVII, PC1251207 (15 June 2023); https://doi.org/10.1117/12.2663934

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