Detecting oesophageal cancer early leads to significantly better patient outcomes. Patients with conditions associated with higher cancer risk undergo regular surveillance endoscopies yet due to low contrast in white light imaging, standard of care endoscopies suffer from low detection rates. Hyperspectral imaging can improve contrast between healthy and diseased tissue. Here, we developed a system enabling flexible illumination-based hyperspectral imaging, designed to be used with a standard clinical endoscope. Our custom light source consists of white light from a supercontinuum laser and one of two tunable illumination systems: an acousto-optic tunable filter, enabling narrowband spectral sweeps, or a high-speed digital micromirror device, resulting in a highly versatile system for clinical testing.
|