Creation of an optically tunable, solid tissue phantom for use in cancer detection

Matthew B. Tucker; Catherine Wallace; Sreekar Mantena; Neil Cornwell; Weston Ross; Ren Odion; Tuan Vo-Dinh; Patrick Codd

doi:10.1117/12.2290499

8 February 2018 Creation of an optically tunable, solid tissue phantom for use in cancer detection

Matthew B. Tucker, Catherine Wallace, Sreekar Mantena, Neil Cornwell, Weston Ross, Ren Odion, Tuan Vo-Dinh, Patrick Codd

Author Affiliations +

Proceedings Volume 10480, Clinical and Translational Neurophotonics 2018; 104800H (2018) https://doi.org/10.1117/12.2290499
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

An optically tunable, solid tissue phantom was developed in order to aid in the verification and validation of non-destructive cancer detection technologies based on fluorescence spectroscopy. The solid tissue phantom contained agarose, hemoglobin, Intralipid, NADH, and FAD. The redox ratio of the solid phantoms were shown to be tunable; thus, indicating that these phantoms could be used to tailor specific optical conditions that mimic cancerous and healthy tissues. Therefore, this solid tissue phantom can serve as a suitable test bed to evaluate fluorescence spectroscopy based cancer detection devices.

Citation Download Citation

Matthew B. Tucker, Catherine Wallace, Sreekar Mantena, Neil Cornwell, Weston Ross, Ren Odion, Tuan Vo-Dinh, and Patrick Codd "Creation of an optically tunable, solid tissue phantom for use in cancer detection", Proc. SPIE 10480, Clinical and Translational Neurophotonics 2018, 104800H (8 February 2018); https://doi.org/10.1117/12.2290499

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available