Automatical and accurate segmentation of cerebral tissues in fMRI dataset with combination of image processing and deep learning

Zhenglun Kong; Junyi Luo; Shengpu Xu; Ting Li

doi:10.1117/12.2293050

13 February 2018 Automatical and accurate segmentation of cerebral tissues in fMRI dataset with combination of image processing and deep learning

Zhenglun Kong, Junyi Luo, Shengpu Xu, Ting Li

Author Affiliations +

Proceedings Volume 10485, Optics and Biophotonics in Low-Resource Settings IV; 104850A (2018) https://doi.org/10.1117/12.2293050
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

Image segmentation plays an important role in medical science. One application is multimodality imaging, especially the fusion of structural imaging with functional imaging, which includes CT, MRI and new types of imaging technology such as optical imaging to obtain functional images. The fusion process require precisely extracted structural information, in order to register the image to it. Here we used image enhancement, morphometry methods to extract the accurate contours of different tissues such as skull, cerebrospinal fluid (CSF), grey matter (GM) and white matter (WM) on 5 fMRI head image datasets. Then we utilized convolutional neural network to realize automatic segmentation of images in deep learning way. Such approach greatly reduced the processing time compared to manual and semi-automatic segmentation and is of great importance in improving speed and accuracy as more and more samples being learned. The contours of the borders of different tissues on all images were accurately extracted and 3D visualized. This can be used in low-level light therapy and optical simulation software such as MCVM. We obtained a precise three-dimensional distribution of brain, which offered doctors and researchers quantitative volume data and detailed morphological characterization for personal precise medicine of Cerebral atrophy/expansion. We hope this technique can bring convenience to visualization medical and personalized medicine.

Conference Presentation

Citation Download Citation

Zhenglun Kong, Junyi Luo, Shengpu Xu, and Ting Li "Automatical and accurate segmentation of cerebral tissues in fMRI dataset with combination of image processing and deep learning", Proc. SPIE 10485, Optics and Biophotonics in Low-Resource Settings IV, 104850A (13 February 2018); https://doi.org/10.1117/12.2293050

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available