Reconstruction of micro CT-like images from clinical CT images using machine learning: a preliminary study

Kyohei Takeda; Yutaro Iwamoto; Keisuke Uemura; Masaki Takao; Nobuhiko Sugano; Yoshinobu Sato; Yen-Wei Chen

doi:10.1117/12.2293443

9 March 2018 Reconstruction of micro CT-like images from clinical CT images using machine learning: a preliminary study

Kyohei Takeda, Yutaro Iwamoto, Keisuke Uemura, Masaki Takao, Nobuhiko Sugano, Yoshinobu Sato, Yen-Wei Chen

Proceedings Volume 10573, Medical Imaging 2018: Physics of Medical Imaging; 1057339 (2018) https://doi.org/10.1117/12.2293443
Event: SPIE Medical Imaging, 2018, Houston, Texas, United States

Abstract

High-resolution medical images are crucial for medical diagnosis, and for planning and assisting surgery. Micro computed tomography (micro CT) can generate high-resolution 3D images and analyze internal micro-structures. However, micro CT scanners can only scan small objects and cannot be used for in-vivo clinical imaging and diagnosis. In this paper, we propose a super-resolution method to reconstruct micro CT-like images from clinical CT images based on learning a mapping function or relationship between the micro CT and clinical CT. The proposed method consists of following three steps: (1) Pre-processing: This involves the collection of pairs of clinical CT images and micro CT images for training and the registration and normalization of each pair. (2) Training: This involves learning a non-linear mapping function between the micro CT and clinical CT by using training pairs. (3) Processing (testing) step: This involves enhancing a new CT image, which is not included in the training data set, by using the learned mapping function.

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Kyohei Takeda, Yutaro Iwamoto, Keisuke Uemura, Masaki Takao, Nobuhiko Sugano, Yoshinobu Sato, and Yen-Wei Chen "Reconstruction of micro CT-like images from clinical CT images using machine learning: a preliminary study", Proc. SPIE 10573, Medical Imaging 2018: Physics of Medical Imaging, 1057339 (9 March 2018); https://doi.org/10.1117/12.2293443

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KEYWORDS

Computed tomography

X-ray computed tomography

Lawrencium

Associative arrays

Image resolution

Super resolution

In vivo imaging

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