Non-invasive blood glucose measurement using quantum cascade lasers

Y. Matsuura; T. Koyama

doi:10.1117/12.2506845

1 February 2019 Non-invasive blood glucose measurement using quantum cascade lasers

Y. Matsuura, T. Koyama

Proceedings Volume 10926, Quantum Sensing and Nano Electronics and Photonics XVI; 1092606 (2019) https://doi.org/10.1117/12.2506845
Event: SPIE OPTO, 2019, San Francisco, California, United States

Abstract

A non-invasive blood glucose measurement method using quantum cascade lasers (QCLs) oscillated in mid-infrared region is introduced. A mid-infrared spectroscopy system equipped with a combination of QCLs as light sources and hollow-optical fibers as beam delivery media is developed. As a wavelength of QCL, the wavenumber of 1152 cm^-1 that exhibited strong correlation with blood glucose in the optical absorption of human lips is firstly chosen. Then 1186 cm^-1 where glucose shows no absorption is also chosen as a reference to remove effects of the baseline variation. By using the QCL-based system, it is shown that the differential absorption between these wavelengths exhibits high correlation with blood glucose level.

Conference Presentation

Citation Download Citation

Y. Matsuura and T. Koyama "Non-invasive blood glucose measurement using quantum cascade lasers", Proc. SPIE 10926, Quantum Sensing and Nano Electronics and Photonics XVI, 1092606 (1 February 2019); https://doi.org/10.1117/12.2506845

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