A linear estimator for timing calibration in time-of-flight PET

Michel Defrise

doi:10.1117/12.2534431

28 May 2019 A linear estimator for timing calibration in time-of-flight PET

Michel Defrise

Proceedings Volume 11072, 15th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine; 110721G (2019) https://doi.org/10.1117/12.2534431
Event: Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine, 2019, Philadelphia, United States

Abstract

We study the performance of a method for the timing calibration of a TOF scanner using arbitrary phantom or patient data. The method uses an initial non TOF reconstruction and estimates the timing offsets of the detectors by weighted least-squares fitting. Assuming bias-free and noise-free estimates of scatter and randoms, the method is shown to yield an unbiased estimate. In addition a theorem and numerical results show that this simple method is close to optimal for the type of phantoms typically used for calibration.

Citation Download Citation

Michel Defrise "A linear estimator for timing calibration in time-of-flight PET", Proc. SPIE 11072, 15th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine, 110721G (28 May 2019); https://doi.org/10.1117/12.2534431

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