Automated readout of a SERS lateral flow assay

Jean-Charles Baritaux; Antoine Hoang; Nathalie Morel

doi:10.1117/12.2527039

19 July 2019 Automated readout of a SERS lateral flow assay

Jean-Charles Baritaux, Antoine Hoang, Nathalie Morel

Proceedings Volume 11073, Clinical and Preclinical Optical Diagnostics II; 1107311 (2019) https://doi.org/10.1117/12.2527039
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

The coupling of Lateral Flow Assays (LFA) to Surface Enhanced Raman Scattering (SERS) readout is promising to obtain field biosensors with exquisite sensitivity. For Point of Care (POC) applications, however, the operation of such a SERSLFA sensor needs to be automated. We developed an acquisition protocol together with a procedure for processing the Raman spectra to address this point. We describe this method and present some results obtained on Ovalbumin as a model target.

Citation Download Citation

Jean-Charles Baritaux, Antoine Hoang, and Nathalie Morel "Automated readout of a SERS lateral flow assay", Proc. SPIE 11073, Clinical and Preclinical Optical Diagnostics II, 1107311 (19 July 2019); https://doi.org/10.1117/12.2527039

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