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Current-generation optical coherence tomographic angiography (OCTA) systems are slit-lamp based, which limits imaging to patients who are able to sit upright and fixate. Prototype handheld OCTA has demonstrated imaging of supine patients, but these systems are susceptible to bulk-motion artifacts that degrade OCTA resolution and contrast. Here, we demonstrate bulk-motion correction and multi-volumetric mosaicking of OCTA volumes acquired using our handheld spectrally encoded coherence tomography and reflectometry (SECTR) system. In addition, we leverage variable-velocity scanning to reduce OCTA acquisition times. We believe SECTR overcomes the limitations of current-generation handheld OCT/OCTA and will enable functional imaging in bedridden patients and infants.
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Eric M. Tang, Joseph D. Malone, Josh Albert H. Miller, Ipek Oguz, Yuankai K. Tao, "Handheld spectrally encoded coherence tomography and reflectometry for point-of-care ophthalmic OCT and OCTA (Conference Presentation)," Proc. SPIE 11228, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXIV, 112280I (9 March 2020); https://doi.org/10.1117/12.2549057