Multi-spectral vascular oximetry of rat dorsal spinal cord

Victor Ochoa-Gutierrez; Pavan C. Konda; Sara Motaghian; Julien Reboud; Jonathan M. Cooper; Andrew R. Harvey

doi:10.1117/12.2558281

21 February 2020 Multi-spectral vascular oximetry of rat dorsal spinal cord

Victor Ochoa-Gutierrez, Pavan C. Konda, Sara Motaghian, Julien Reboud, Jonathan M. Cooper, Andrew R. Harvey

Proceedings Volume 11230, Optics and Biophotonics in Low-Resource Settings VI; 1123012 (2020) https://doi.org/10.1117/12.2558281
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

We describe a visible-light multi-spectral system for vascular oximetry studies that can be implemented in lowand middle-income countries, using a low-cost electronics and optical elements, for instance a Raspberry Pi, a Pi camera under a resolution of 5-megapixel, 2592x1944-pixel resolution, and four different light sources at 480nm, 532nm, 593nm and 610nm on a singular structured illumination area. It is designed to quantify the vascular oxygen saturation change of the rat dorsal spinal cord, which uses a Phyton custom application that synchronize all elements to execute the imaging process in one system, powered by a portable rechargeable 5V battery pack. Aimed for drug discovery, tracking disease progression and understanding of progressive and degenerative diseases. By replacing expensive and bulky imaging systems.

Citation Download Citation

Victor Ochoa-Gutierrez, Pavan C. Konda, Sara Motaghian, Julien Reboud, Jonathan M. Cooper, and Andrew R. Harvey "Multi-spectral vascular oximetry of rat dorsal spinal cord", Proc. SPIE 11230, Optics and Biophotonics in Low-Resource Settings VI, 1123012 (21 February 2020); https://doi.org/10.1117/12.2558281

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