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17 February 2020 Enhancement of Xe-NMR signals at low magnetic field using optical pumping hyperpolarization
Shun Takeda, Hiroshi Kumagai, Mineyuki Hattori
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Proceedings Volume 11243, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVIII; 112431W (2020) https://doi.org/10.1117/12.2544572
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
In recent years, MRI using a rare gas has attracted attention. Rare gas MRI can perform imaging of lungs with few protons and can also evaluate gas dynamics and hemodynamics. Attempts have been made to enhance the signal intensity by hyperpolarizing nuclear spins to obtain NMR signals from the gas. This hyperpolarization technology is also expected to be effective when combined with low-field MRI including permanent magnet type. In this study, a xenon (129Xe) hyperpolarization system using a 795nm laser was constructed and evaluated using a 0.3T NMR system. As a result, it was shown that the NMR signal intensity from 129Xe can be enhanced 1.5 times with a polarization of 30 minutes.
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Shun Takeda, Hiroshi Kumagai, and Mineyuki Hattori "Enhancement of Xe-NMR signals at low magnetic field using optical pumping hyperpolarization", Proc. SPIE 11243, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVIII, 112431W (17 February 2020); https://doi.org/10.1117/12.2544572
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KEYWORDS
Xenon
Polarization
Magnetic resonance imaging
Rubidium
Optical pumping
Noble gases
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