Low-cost glucose biosensor fabricated by a photosensitive resin that features nanoparticles

J. V. Guzmán; M. I. Saldana; A. A. Polokhin; A. A. Castillo; V. Guzman

doi:10.1117/12.2546938

21 February 2020 Low-cost glucose biosensor fabricated by a photosensitive resin that features nanoparticles

J. V. Guzmán, M. I. Saldana, A. A. Polokhin, A. A. Castillo, V. Guzman

Proceedings Volume 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII; 112541C (2020) https://doi.org/10.1117/12.2546938
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

A low-cost biosensor for glucose analysis was designed, fabricated and characterized. It was fabricated by using a DLPdirect light processing, 3D printed technique. The operation principle for the electro-optic device is based on the total internal reflection. The photosensitive resin is considered that is doped with nanoparticles such as quantum dots and carbon nanotubes as a waveguide. By using DLP 3D printing technique the device was fabricated. The operation principle was based on the optical phase shift. The entire structure of the device features a Mach-Zehnder Interferometer (MZI) that was numerically analyzed in a commercial software featuring finite element. The biosensor works in the transmission scheme. Mach-Zehnder interferometer is composed of a waveguide that encompasses the resin doped with nanodots that linked both input and output signals. In contrast, one arm is kept isolated and the other arm exposed to the medium in order to obtain the phase change at the MZI output. A laser-diode of 980 nm was considered as the source. The optical array features a single-mode optic fiber and a bidirectional coupler. While tested, several glucose concentrations (from 0% to 3%) were provided in order to determine the relationship between the glucose concentration and the output signal in order to increase the sensitivity. The future possibility of the aforementioned structure describes the use of several materials for biological-related applications are also discussed.

Citation Download Citation

J. V. Guzmán, M. I. Saldana, A. A. Polokhin, A. A. Castillo, and V. Guzman "Low-cost glucose biosensor fabricated by a photosensitive resin that features nanoparticles", Proc. SPIE 11254, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XVII, 112541C (21 February 2020); https://doi.org/10.1117/12.2546938

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available