Correlation between retinal ganglion layer soma and vascular densities measured with adaptive optics: optical coherence tomography

Ricardo Villanueva; Zhuolin Liu; Furu Zhang; Daniel Hammer; Osamah J. Saeedi

doi:10.1117/12.2583198

5 March 2021 Correlation between retinal ganglion layer soma and vascular densities measured with adaptive optics: optical coherence tomography

Ricardo Villanueva, Zhuolin Liu, Furu Zhang, Daniel Hammer, Osamah J. Saeedi

Author Affiliations +

Proceedings Volume 11623, Ophthalmic Technologies XXXI; 116230K (2021) https://doi.org/10.1117/12.2583198
Event: SPIE BiOS, 2021, Online Only

Abstract

Glaucoma is an optic neuropathy characterized by loss of retinal ganglion cells and their axons. Glaucoma has a strong vascular component and decreased macular vessel density is known to be associated with glaucomatous damage. Adaptive optics – optical coherence tomography allows for the simultaneous quantification of vascular and ganglion cell densities. We observed a moderately strong correlation between ganglion cell and vessel densities across the macula, as well as some correlation at individual locations. Vascular density may prove to be a useful surrogate biomarker of glaucoma progression and with further study reveal new information on impairment of neurovascular coupling in glaucoma.

Conference Presentation

Citation Download Citation

Ricardo Villanueva, Zhuolin Liu, Furu Zhang, Daniel Hammer, and Osamah J. Saeedi "Correlation between retinal ganglion layer soma and vascular densities measured with adaptive optics: optical coherence tomography", Proc. SPIE 11623, Ophthalmic Technologies XXXI, 116230K (5 March 2021); https://doi.org/10.1117/12.2583198

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available